Roles of OLR1 and IL17A variants on clinical phenotypes of Turkish patients undergoing coronary artery bypass surgery

Autor: Recep Eymen, Bayoglu Burcu, Arslan Caner, Goksedef Deniz, Ipek Gokhan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Türk Biyokimya Dergisi, Vol 47, Iss 5, Pp 571-579 (2022)
Druh dokumentu: article
ISSN: 1303-829X
DOI: 10.1515/tjb-2021-0214
Popis: Coronary artery disease (CAD) is a pathological condition resulting from atherosclerosis in the coronary arteries. IL17A has been shown to recruit and activate macrophages in atherosclerotic lesions, thereby participating in plaque destabilization. Currently, whether OLR1 and IL17A variants are involved in the pathogenesis of CAD is unclear. This case-control study aimed to investigate their roles in CAD etiology and prognosis.
Databáze: Directory of Open Access Journals