Quantitative computed tomography and visual emphysema scores: association with lung function decline
| Autor: | Meghan C. Koo, Wan C. Tan, Jim C. Hogg, Jean Bourbeau, Cameron J. Hague, Jonathon A. Leipsic, Miranda Kirby |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | ERJ Open Research, Vol 9, Iss 2 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2312-0541 23120541 |
| DOI: | 10.1183/23120541.00523-2022 |
| Popis: | Background Computed tomography (CT) visual emphysema score is a better predictor of mortality than single quantitative CT emphysema measurements in COPD, but there are numerous CT measurements that reflect COPD-related disease features. The purpose of this study was to determine if linear combinations of quantitative CT measurements by principal component analysis (PCA) have a greater association with forced expiratory volume in 1 s (FEV1) lower limit of normal (LLN) annualised change (ΔFEV1) than visual emphysema score in COPD. Methods In this retrospective, longitudinal study, demographic, spirometry and CT images were acquired. CT visual emphysema score and quantitative analysis were performed; low attenuation area |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|