Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice
Autor: | Shinya Sakai, Hiroshi Ochiai, Naoki Mantani, Toshiaki Kogure, Naotoshi Shibahara, Katsutoshi Terasawa |
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Jazyk: | angličtina |
Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Mediators of Inflammation, Vol 10, Iss 2, Pp 93-96 (2001) |
Druh dokumentu: | article |
ISSN: | 0962-9351 1466-1861 |
DOI: | 10.1080/09629350120054572 |
Popis: | Background: Isoferulic acid (IFA) is a main active ingredient of the rhizoma of Cimicifuga heracleifolia, which is used frequently in Japanese traditional medicine as an anti-inflammatory drug. It has been revealed that IFA inhibits the production of macrophage inflammatory protein-2 (MIP-2), which is a murine counterpart of the chemokine family that may contribute to the pathogenesis of inflammatory diseases through the chemotactic activity for inflammatory and immune effector cells. |
Databáze: | Directory of Open Access Journals |
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