Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice

Autor:	Shinya Sakai, Hiroshi Ochiai, Naoki Mantani, Toshiaki Kogure, Naotoshi Shibahara, Katsutoshi Terasawa
Jazyk:	angličtina
Rok vydání:	2001
Předmět:	Pathology RB1-214
Zdroj:	Mediators of Inflammation, Vol 10, Iss 2, Pp 93-96 (2001)
Druh dokumentu:	article
ISSN:	0962-9351 1466-1861
DOI:	10.1080/09629350120054572
Popis:	Background: Isoferulic acid (IFA) is a main active ingredient of the rhizoma of Cimicifuga heracleifolia, which is used frequently in Japanese traditional medicine as an anti-inflammatory drug. It has been revealed that IFA inhibits the production of macrophage inflammatory protein-2 (MIP-2), which is a murine counterpart of the chemokine family that may contribute to the pathogenesis of inflammatory diseases through the chemotactic activity for inflammatory and immune effector cells.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5752227f4a59460d94bdc6d6b1176b3b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF