Multidrug-Resistant Escherichia coli Causing Urinary Tract Infections among Controlled and Uncontrolled Type 2 Diabetic Patients at Laquintinie Hospital in Douala, Cameroon

Autor: Josiane Claire Sonkoue Lambou, Michel Noubom, Boris Emmanuel Djoumsie Gomseu, Wiliane Jean Takougoum Marbou, Jean-De-Dieu Tamokou, Donatien Gatsing
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 1918-1493
DOI: 10.1155/2022/1250264
Popis: Urinary tract infections (UTIs) in patients with diabetes are a major public health problem worldwide, particularly in developing countries. This study assessed the resistance profile of Escherichia coli and biochemical abnormalities in controlled and uncontrolled type 2 diabetic patients. A cross-sectional study was conducted at the Douala Laquintinie Hospital from January, 2020, to July, 2021, on the diabetic and nondiabetic participants. The clinical symptoms and biochemical parameters of patient having UTIs were measured using standard methods. E. coli was isolated from urine and an antibiotic susceptibility test was performed using the Kirby-Bauer Agar diffusion method. A total of 851 participants were included with a mean age of 48.54 years. Three hundred and forty-six (40.67%) were nondiabetic, 226 (26.56%) were diabetic patients with balanced blood sugar levels (i.e., glycosylated haemoglobin (HbA1c) is normal), and 279 (32.78%) were diabetic patients with unbalanced blood sugar levels (i.e., patients having an abnormal HbA1c). The prevalence of UTI caused by E. coli was significantly (p
Databáze: Directory of Open Access Journals
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