Use of naproxen versus intracervical block for pain control during the 52-mg levonorgestrel-releasing intrauterine system insertion in young women: a multivariate analysis of a randomized controlled trial

Autor: Elaine Cristina Fontes de Oliveira, Thaís Baêta, Ana Paula Caldeira Brant, Agnaldo Silva-Filho, Ana Luiza Lunardi Rocha
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Women's Health, Vol 21, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 1472-6874
DOI: 10.1186/s12905-021-01521-z
Popis: Abstract Background To compare the effectiveness of 550 mg naproxen sodium versus 6 mL 2%-lidocaine intracervical block in pain lowering at the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) placement in young women. Methods In this randomized controlled trial, 100 women aged 15–24 years were block-randomized to receive either 6 mL 2%-lidocaine intracervical block 5 min before the LNG-IUS insertion or 550 mg naproxen 30 min before the procedure. Forty-nine women received 550 mg naproxen and 51 received intracervical block. The primary outcome was pain at LNG-IUS insertion. Secondary outcomes were ease of insertion, insertion failures, and correct IUS positioning. Neither participants nor doctors were blinded. Pain at insertion was assessed by using a Visual Analog Scale (VAS). Results Women randomized to lidocaine intracervical block presented lower mean pain score at insertion, when compared to women who received naproxen (5.4 vs. 7.3, respectively; p
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