Highlights on polymeric micelles as versatile nanocarriers for drug transporting

Autor:	Hussein A. Abdul Hussein, Nidhal K. Maraie
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	amphiphilic copolymers critical micelle concentration solubilization drug delivery drug targeting and polymeric micelles Pharmacy and materia medica RS1-441
Zdroj:	Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 21, Iss 2 (2022)
Druh dokumentu:	article
ISSN:	1815-0993 2959-183X
DOI:	10.32947/ajps.v21i2.806
Popis:	Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium. PMs characterized by small size, spherical shape, lower critical micellar concentration, which gave higher stability for PMs over conventional surfactant micelles. The core/shell structure permits polymeric micelle to entrap poor soluble drugs and can improve their solubility and permeability. The preparation of PMs tends to be relatively easy as compared to other novel drug delivery systems. This review focus on the general properties, types, types of copolymer utilized, formation mechanism, preparation methods, characterization techniques, and the applications on PMs.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/56fe3fe7ac9347a6a827e00987bf2cd2 Zobrazit plný text záznamu View record in DOAJ