Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles

Autor: Tengfei Kang, Liuzhen Hou, Sai Ruan, Weidi Cao, Xiaohua Liu, Xiaoming Feng
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17681-9
Popis: The investigation of reactivity of β,γ-unsaturated carbonyl compounds is of great synthetic value, especially in asymmetric transformations. Here, the authors report a catalytic asymmetric tandem isomerization/α-Michael addition of β,γ-unsaturated 2-acyl imidazoles in presence of chiral N,N′-dioxide metal catalysts.
Databáze: Directory of Open Access Journals