| Autor: |
Jeong Mi Hwang, Su Jung Choi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Asian Nursing Research, Vol 17, Iss 1, Pp 15-22 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1976-1317 |
| DOI: |
10.1016/j.anr.2022.12.002 |
| Popis: |
sum mary: Purpose: This study aimed to identify the early sedation depth in the first 48 hours of mechanical ventilation and its relationship to clinical outcomes to promote the transition to light sedation. Methods: This retrospective single-center cohort study was conducted in two medical intensive care units (MICUs) at a general tertiary hospital, using a standardized sedation protocol. To investigate the early sedation depth, the Sedation Index was used, which can indicate changes over the first 48 hours. Patients were divided into three groups based on tertiles of Sedation Index. The primary outcome was mortality at 30, 90, and 180 days. The secondary outcomes included length of stay in the ICU and ventilator-free days. Kaplan-Meier analysis and multivariable Cox regression were conducted to compare factors influencing mortality. Results: This study included 394 patients. The deepest sedation group showed more severe illness, delirium, and deeper sedation at admission (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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