Quasi-Stationary Approximation of a Dynamical Model of MicroRNA Target Regulation. Part II. Application of the QSSA Theorem

Autor:	Nikolova E., Herwig R., Petrov V.
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	QSSA theorem MicroRNA target regulation Proteins Post-initial state Biotechnology TP248.13-248.65 Biology (General) QH301-705.5
Zdroj:	Bioautomation, Vol 13, Iss 4, Pp 135-142 (2009)
Druh dokumentu:	article
ISSN:	1313-261X 1312-451X
Popis:	The QSSA theorem is applied to the dynamical model of microRNA target regulation after special selection of model variables, presented in Part I of this article. On the basis of this theorem the complete model, represented as a system of seven nonlinear ordinary differential equations, is reduced to a degenerate one, comprising only two ordinary differential equations. As a result it is proved that the proteins, produced by miRNAs are identified to play a driving role of the dynamical behaviour of the genetic process investigated, but in post-initial (or quasi-stationary) stage.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/56eb98d5aeb34a7b969fe55248c5ffa3 Zobrazit plný text záznamu View record in DOAJ