Antiretroviral treatment failure and associated factors among HIV patients on first-line antiretroviral treatment in Sekota, northeast Ethiopia

Autor: Jemberu Nega, Solomon Taye, Yihenew Million, Chaturaka Rodrigo, Setegn Eshetie
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 1742-6405
DOI: 10.1186/s12981-020-00294-z
Popis: Abstract Background Antiretroviral treatment has played a pivotal role in the reduction of HIV/AIDS-related morbidity and mortality. However, treatment options can be impaired by the development of antiretroviral treatment failure. Regular monitoring of the Human Immunodeficiency Virus treatment outcome via viral load tests is the key approach. There is a scarcity of information about HIV treatment failure and risk factors in the study area. Therefore, the study was aimed to assess antiretroviral treatment failure and associated factors among patients on first-line antiretroviral treatment at Tefera Hailu Memorial Hospital, Sekota, northeast Ethiopia. Methods A hospital-based cross-sectional study was conducted on 295 patients on first-line antiretroviral treatment from Nov. 2018 to Apr. 2019. Socio-demographic and clinical variables were collected using a pretested questionnaire, and blood specimen was collected for PCR viral load and CD4 + cell count estimation. Data were entered into Epi-Info and exported to SPSS for analysis. A binary logistic regression model was used to identify associated factors, and P value
Databáze: Directory of Open Access Journals
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