Autor: |
Qi Wang, Yang Zhang, Bolei Zhang, Yao Fu, Xiaozhi Zhao, Jing Zhang, Ke Zuo, Yuexian Xing, Song Jiang, Zhaohui Qin, Erguang Li, Hongqian Guo, Zhihong Liu, Jingping Yang |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-021-27660-3 |
Popis: |
The heterogeneity of cell-of-origin for papillary renal cell carcinoma (pRCC) remains unknown. Here, with single-cell ATAC-seq from normal human kidney cells and ATACseq profiles from pRCC samples, the authors show that pRCC can originate from kidney collecting duct principal cells and this subtype is associated with advanced pRCC. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|