Unveiling post-MIS-N cardiomyopathy by longitudinal multimodality global cardiac assessment from neonatal insult to 16-month follow-up

Autor: Maitri Chaudhuri, Munesh Tomar, Balasubramanyam Shankar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Pediatric Cardiology, Vol 16, Iss 6, Pp 463-467 (2023)
Druh dokumentu: article
ISSN: 0974-2069
0974-5149
DOI: 10.4103/apc.apc_114_23
Popis: A full-term male neonate presented on the 11th day of life with late-onset multisystem inflammatory syndrome-neonate (MIS-N) (cardioneurological compromise). Immediate anti-inflammatory modulation led to a gradual recovery of neurological and coronary lesions. However, temporal evaluation unmasked silent myocardial dysfunction in echocardiography validated further by elevated biomarkers, myocardial fibrosis in cardiac magnetic resonance imaging, and abnormal strain study persisting till 16 months of follow-up. This revealed a hitherto unknown and rare progression of MIS-N into dilated cardiomyopathy.
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