Cardiovascular health profiles in adolescents being born term or preterm—results from the EVA-Tyrol study

Autor: Christoph Hochmayr, Jean-Pierre Ndayisaba, Nina Gande, Anna Staudt, Benoit Bernar, Katharina Stock, Sophia J. Kiechl, Ralf Geiger, Elke Griesmaier, Michael Knoflach, Ursula Kiechl-Kohlendorfer, Early Vascular Ageing (EVA) Study Group
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-023-03360-2
Popis: Abstract Background and aims Preterm birth has been linked with an increased risk of cardiovascular (CV) disease from childhood into adolescence and early adulthood. In this study, we aimed to investigate differences in CV health profiles between former term- and preterm-born infants in a cohort of Tyrolean adolescents. Methods The Early Vascular Aging (EVA)-Tyrol study is a population-based non-randomized controlled trial, which prospectively enrolled 14- to 19-year-old adolescents in North Tyrol, Austria and South Tyrol, Italy between 2015 and 2018. Metrics of CV health (body mass index (BMI), systolic (SBP) and diastolic blood pressure (DBP), smoking, physical activity, dietary patterns, total cholesterol and fasting blood glucose) were assessed and compared between former term- and preterm-born girls and boys. Results In total, 1,491 study participants (59.5% female, mean age 16.5 years) were included in the present analysis. SBP and DBP were significantly higher in former preterm-born adolescents (mean gestational age 34.6 ± 2.4 weeks) compared to term-born controls (p
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