Higher prevalence of kidney function impairment among older people living with HIV in Uganda

Autor: Amutuhaire Judith Ssemasaazi, Robert Kalyesubula, Yukari C. Manabe, Phoebe Mbabazi, Susan Naikooba, Faizo Ssekindi, Esther Nasuuna, Pauline Byakika-Kibwika, Barbara Castelnuovo
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-024-03761-1
Popis: Abstract Background People living with HIV (PLWH) are at risk of kidney function impairment due to HIV-related inflammation, antiretroviral therapy (ART), diabetes mellitus, and hypertension. Older persons may experience a higher burden of chronic kidney disease (CKD) as kidney function declines with increasing age. There is a paucity of data comparing the prevalence of kidney function impairment in older PLWH to that in people without HIV in sub-Saharan Africa. Methods We conducted a cross-sectional study among people aged ≥ 60 years living with and without HIV in Kampala, Uganda who were matched 1:1 by community location. We collected data on sociodemographics, comorbidities, and HIV-related clinical characteristics. We defined kidney function impairment as an estimated glomerular filtration rate(eGFR)
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