TYPE 1 DIABETES AND INSULIN RESISTANCE: ESTIMATED GLUCOSE DISPOSAL RATE AND ITS CORRELATION WITH CHRONIC COMPLICATIONS

Autor: Gabriela Caeiro, Silvana A Romero Gónzalez, Jimena Itria, Jorge Waitman
Jazyk: Spanish; Castilian
Rok vydání: 2018
Předmět:
Zdroj: Revista de la Sociedad Argentina de Diabetes, Vol 51, Iss 2, Pp 38-46 (2018)
Druh dokumentu: article
ISSN: 0325-5247
2346-9420
DOI: 10.47196/diab.v51i2.53
Popis: Introduction: insulin resistance (IR) in type 1 diabetes (T1D) is associated with a higher risk of complications in these patients. The gold standard for measuring insulin sensitivity is the hyperinsulinemic-euglycemic clamp although not used in clinical practice. The estimated glucose disposal rate (eGDR) has been validated to estimate insulin sensitivity. Objectives: the objective was to correlate IR in T1D (eGDR), with macro and microvascular complications in patients assisted in a Diabetology Service. Materials and methods: we performed a cross-sectional study. The eGDR was calculated using HbA1c, waist circumference, and hypertensive status.
Databáze: Directory of Open Access Journals