Laser-assisted hatching in lower grade cleavage stage embryos improves blastocyst formation: results from a retrospective study

Autor: Weihai Xu, Ling Zhang, Lin Zhang, Zhen Jin, Limei Wu, Shishi Li, Jing Shu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1757-2215
DOI: 10.1186/s13048-021-00844-7
Popis: Abstract Background Laser-assisted hatching (LAH) has been widely applied to facilitate blastocyst hatching in IVF-ET treatment, however, the effect of LAH on subsequent development and clinical outcomes of the lower grade cleavage stage embryos (LGCE) remains unknown. Our study aimed at evaluating the effect of LAH on blastocyst formation and the clinical pregnancy outcomes of LGCE embryos after transfer. Methods A total of 608 cycles of IVF/ICSI treatment from November 2017 to September 2019 were included in our study as follows: 296 in the LAH group and 312 in the N-LAH group. The total blastocyst rate, usable blastocyst rate, good-grade blastocyst rate and clinical pregnancy rate were statistically compared between the two groups. Results The total blastocyst rate (50.7% vs 40.2%, P 0.05, respectively). Conclusions A higher proportion of total blastocysts and usable blastocysts can be obtained by LAH in LGCE, which may be beneficial to the outcome of the IVF/ICSI-ET cycle.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje