| Autor: |
Hyun Seok, Seong-Gon Kim, Min-Keun Kim, Insan Jang, Janghoon Ahn |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Maxillofacial Plastic and Reconstructive Surgery, Vol 40, Iss 1, Pp 1-8 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2288-8586 |
| DOI: |
10.1186/s40902-018-0146-4 |
| Popis: |
Abstract Background The objective of this study was to evaluate the influence of masticatory muscle injection of botulinum toxin type A (BTX-A) on the growth of the mandibular bone in vivo. Methods Eleven Sprague-Dawley rats were used, and BTX-A (n = 6) or saline (n = 5) was injected at 13 days of age. All injections were given to the right masseter muscle, and the BTX-A dose was 0.5 units. All of the rats were euthanized at 60 days of age. The skulls of the rats were separated and fixed with 10% formalin for micro-computed tomography (micro-CT) analysis. Results The anthropometric analysis found that the ramus heights and bigonial widths of the BTX-A-injected group were significantly smaller than those of the saline-injected group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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