Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran
| Autor: | Miaad K Alkhudhairy, Morteza Saki, Sakineh Seyed–Mohammadi, Nabi Jomehzadeh, Saeed Khoshnood, Mina Moradzadeh, Sajjad Yazdansetad |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of Acute Disease, Vol 8, Iss 3, Pp 113-117 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2221-6189 2589-5516 |
| DOI: | 10.4103/2221-6189.259110 |
| Popis: | Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P |
| Databáze: | Directory of Open Access Journals |
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