The Advanced Age is Effective on Recurrence and Progression in Patients With Non-Muscle Invasive Bladder Cancer
| Autor: | Goksel Bayar, Muhammet Fatih Kilinc |
|---|---|
| Jazyk: | English<br />Turkish |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Yeni Üroloji Dergisi, Vol 15, Iss 3, Pp 171-175 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1305-2489 2687-1955 |
| DOI: | 10.33719/yud.638579 |
| Popis: | Objective: To evaluate the effect of age on recurrence and progression in patients with primary and non-muscle invasive bladder cancer (NMIBC). Material and Methods: The records of patients who underwent transurethral bladder tumor resection (TUR-BT) for primary bladder tumor between 2005-2010 were retrospectively reviewed. Patients who had NMIBC after the first TUR-BT and without extra-bladder involvement were included in the study. The patients were grouped in terms of age (under 60 years, 60-70 years, over 70 years), sex, tumor size (below and above 3 cm); the number of tumors (between 1, 2-7 and> 7); stage (Ta and T1) and grade (G1, G2 and G3). Results: A total of 316 patients were included in the study. Recurrence was seen in 226 (71.5%) and progression 71 patients (22.5%). Univariate analysis showed that age (> 70), tumor number (> 1), size (> 3 cm), stage (T1) and grade (G3) are effective in the development of recurrence and progression. Kaplan-Meier analysis showed that there was a significant difference between the age groups in terms of time to recurrence (p = 0.001), as age increased the probability of recurrence increased and time to recurrence decreased. There was a significant difference between the groups in the progression analysis and that the risk of progression increased with age and the time to progression decreased (p = 0.004). Conclusions: We found that the probability of recurrence and progression was significantly increased with age, especially over 70 years of age, in patients with NMIBC. |
| Databáze: | Directory of Open Access Journals |
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