| Autor: |
Narine Mesropyan, Patrick A. Kupczyk, Leona Dold, Michael Praktiknjo, Johannes Chang, Alexander Isaak, Christoph Endler, Dmitrij Kravchenko, Leon M. Bischoff, Alois M. Sprinkart, Claus C. Pieper, Daniel Kuetting, Christian Jansen, Ulrike I. Attenberger, Julian A. Luetkens |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-13340-9 |
| Popis: |
Abstract We aimed to investigate the diagnostic utility of MRI extracellular volume fraction (ECV) for the assessment of liver cirrhosis severity as defined by Child–Pugh class. In this retrospective study, 90 patients (68 cirrhotic patients and 22 controls), who underwent multiparametric liver MRI, were identified. Hepatic T1 relaxation times and ECV were assessed. Clinical scores of liver disease severity were calculated. One-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test, Spearman’s correlation coefficient, and receiver operating characteristic (ROC) analysis were used for statistical analysis. In cirrhotic patients, hepatic native T1 increased depending on Child–Pugh class (620.5 ± 78.9 ms (Child A) vs. 666.6 ± 73.4 ms (Child B) vs. 828.4 ± 91.2 ms (Child C), P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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