Diagnostic accuracy of point-of-care ultrasound with artificial intelligence-assisted assessment of left ventricular ejection fraction

Autor: Pouya Motazedian, Jeffrey A. Marbach, Graeme Prosperi-Porta, Simon Parlow, Pietro Di Santo, Omar Abdel-Razek, Richard Jung, William B. Bradford, Miranda Tsang, Michael Hyon, Stefano Pacifici, Sharanya Mohanty, F. Daniel Ramirez, Gordon S. Huggins, Trevor Simard, Stephanie Hon, Benjamin Hibbert
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: npj Digital Medicine, Vol 6, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 2398-6352
DOI: 10.1038/s41746-023-00945-1
Popis: Abstract Focused cardiac ultrasound (FoCUS) is becoming standard practice in a wide spectrum of clinical settings. There is limited data evaluating the real-world use of FoCUS with artificial intelligence (AI). Our objective was to determine the accuracy of FoCUS AI-assisted left ventricular ejection fraction (LVEF) assessment and compare its accuracy between novice and experienced users. In this prospective, multicentre study, participants requiring a transthoracic echocardiogram (TTE) were recruited to have a FoCUS done by a novice or experienced user. The AI-assisted device calculated LVEF at the bedside, which was subsequently compared to TTE. 449 participants were enrolled with 424 studies included in the final analysis. The overall intraclass coefficient was 0.904, and 0.921 in the novice (n = 208) and 0.845 in the experienced (n = 216) cohorts. There was a significant bias of 0.73% towards TTE (p = 0.005) with a level of agreement of 11.2%. Categorical grading of LVEF severity had excellent agreement to TTE (weighted kappa = 0.83). The area under the curve (AUC) was 0.98 for identifying an abnormal LVEF (
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