CLINICAL PREDICTORS OF LOW BONE MINERAL DENSITY IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS
| Autor: | M M Kostik, V I Larionova, L A Scheplyagina |
|---|---|
| Jazyk: | English<br />Russian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Остеопороз и остеопатии, Vol 17, Iss 2, Pp 11-15 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2072-2680 2311-0716 |
| DOI: | 10.14341/osteo2014211-15 |
| Popis: | The aim of this study was to assess the role of simple clinical and laboratorial markers for prediction of low bone mineral density (LBMD < -2 SD) in children with juvenile idiopathic arthritis (JIA). Low weight and linear growth ( 5.0, DAS > 2.9, DAS28 > 4.2, JADAS 10 > 15.6, JADAS 27 > 15.1, CDAI > 18.1, Steinbrocker's functional class > 2, systemic arthritis, corticosteroid treatment, arthritis duration > 4.5 years, number of active joints > 5, number of painful joints > 9, morning stiffness > 90 minutes, parental overall JIA activity (VAS) > 5.8, ESR > 16 mm/h, CRP > 22.6 mg/l were associated with increased risk of LBMD in JIA children. Among metabolic markers Ca total < 2.42 mmol/l and Pi > 1.59 mmol/l also increased the possibility of LBMD. Our data can help to identify the JIA patients at risk for LBMD and to suggest the indications for densitometry evaluation of JIA children. |
| Databáze: | Directory of Open Access Journals |
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