Addition of CFCl3 to Aromatic Aldehydes via in Situ Grignard Reaction

Autor: Balaka Barkakaty, Bandana Talukdar, Bradley S. Lokitz
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Molecules, Vol 20, Iss 8, Pp 15098-15107 (2015)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules200815098
Popis: Synthetic modification of trichlorofluoromethane (CFCl3) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for in situ Grignard reaction using magnesium powder and CFCl3 for synthesis of dichlorofluoromethyl aromatic alcohols.
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