| Autor: |
Yigit Uyanikgil, Turker Cavusoglu, Kubilay Dogan Kılıc, Gurkan Yigitturk, Servet Celik, Richard Shane Tubbs, Mehmet Turgut |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Journal of Brachial Plexus and Peripheral Nerve Injury, Vol 12, Iss 01, Pp e1-e6 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1749-7221 |
| DOI: |
10.1055/s-0036-1597838 |
| Popis: |
Abstract This review summarizes the role of melatonin (MLT) in defense against toxic-free radicals and its novel effects in the development of the nervous system, and the effect of endogenously produced and exogenously administered MLT in reducing the degree of tissue and nerve injuries. MLT was recently reported to be an effective free radical scavenger and antioxidant. Since endogenous MLT levels fall significantly in senility, these findings imply that the loss of this antioxidant could contribute to the incidence or severity of some age-related neurodegenerative diseases. Considering the high efficacy of MLT in overcoming much of the injury not only to the peripheral nerve but also to other organs, clinical trials for this purpose should be seriously considered. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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