1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp.

Autor: María Jesús Martín, Laura Coello, Fernando Reyes
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Marine Drugs, Vol 7, Iss 3, Pp 445-450 (2009)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md7030445
Popis: A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the μM level against three human tumor cell lines.
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