Urinary tract infections and antimicrobial susceptibility pattern among female students in a tertiary institution in southwest Nigeria - A cross sectional study

Autor: Tinuade Adesola Ajani, Charles John Elikwu, Victor Ugochukwu Nwadike, Babatunde Tayo, Opeoluwa Akinleye Shonekan, Celen Chika Okangba, Chinenye Gloria Anaedobe, Tunde Ehimen Thompson, Azubuike Chidiebere Omeonu, Faluyi Bibitayo, Mustapha Akanji Ajani, Nkadinma Florence Nkwogu, Joseph Emejuru, Kelechi Okangba, Obinna Mark Ugwa, Marvelous Afolabi, Abisola Atere, Temidola Kalejaye, Timothy A Oluwasola, Olusegun Akintoye Coker
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical Sciences, Vol 17, Iss 4, Pp 131-135 (2020)
Druh dokumentu: article
ISSN: 2468-6859
2408-7408
DOI: 10.4103/jcls.jcls_47_19
Popis: Background: Urinary tract infections (UTIs) is a common medical problem that affects all age groups but with significant morbidity in females because of the nature of their anatomy and physiology. This study was aimed to identify the common causative organisms of UTI and their antimicrobial susceptibility pattern among female students in Babcock University. Methods: A cross-sectional study, in which 200 female participants with symptoms of UTI were recruited. Mid-stream urine was collected from them and processed using the standard microbiological procedures. Antimicrobial susceptibility testing was performed on isolates from the samples with significant bacteriuria. Sociodemographic and risk factors were obtained using standard questionnaires, and statistical analysis was performed using SPSS version 23.0. Results: UTIs were confirmed in 14.5% (29/200) participants. Of the pathogens isolated, Escherichia coli was predominant 30.6% (11/36). Most of the pathogens isolated were susceptible to ofloxacin and gentamicin, while ceftriaxone had the least susceptibility (18.2%). The majority of the participants, 165 (82.5%) though symptomatic, did not have bacteriuria. The participants aged 15–20 years were mostly infected [24 (13.4%)]. No significant association was found between the sociodemographic factors and UTI. Conclusion: The prevalence of UTI from this study was 14.5%. E. coli was the predominant bacteria pathogen isolated, and ofloxacin and gentamycin were the most active antibiotics on susceptibility pattern. The majority of the patients though symptomatic, had no pathogens isolated from their urine. Therefore, caution should be applied on the use of antibiotics when managing UTI based on symptoms alone, to prevent antibiotic resistance
Databáze: Directory of Open Access Journals
Externí odkaz: