Autor: |
Qing Zhang, Liyan Jian, Deqiang Yao, Bing Rao, Ying Xia, Kexin Hu, Shaobai Li, Yafeng Shen, Mi Cao, An Qin, Jie Zhao, Yu Cao |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-023-37557-y |
Popis: |
Cells maintain a narrow physiological pH by exchanging intracellular bicarbonate for extracellular chloride. Here, authors determine the cryo-EM structures of human anion exchanger 2 (AE2) in five major operating states and one transitional state, to collectively demonstrate the process of pH-balancing. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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