CONTEMPORARY APPROACHES TO LEVOTHYROXINE THERAPY AFTER SURGERY IN PATIENTS WITH WELL-DIFFERENTIATED THYROID CANCER

Autor:	P. O. Rumyantsev, S. V. Korenev, U. V. Rumyantseva
Jazyk:	ruština
Rok vydání:	2015
Předmět:	thyroid cancer thyrotropic hormone levothyroxine suppressive therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Опухоли головы и шеи, Vol 0, Iss 2, Pp 5-8 (2015)
Druh dokumentu:	article
ISSN:	2222-1468 2411-4634
DOI:	10.17650/2222-1468-2013-0-2-5-8
Popis:	Levothyroxine therapy with purpose to suppress thyroid stimulating hormone (TSH) after surgery in patients with well-differentiated thyroid cancer is implemented since 1937. Accumulated results of levothyroxine suppressive therapy (LST) application are attesting its heterogeneous efficacy in various risk groups of tumor recurrence: low, medium and high. Similar risk groups are emphasized towards adverse effect risk due to LST. The more intensivity and duration of TSH suppression the higher risk of adverse effects. First, they include osteopenia or osteoporosis and atrial fibrillation. Contemporary approaches to intensivity and duration of LTS are based on accounting of its potential efficiency into various clinical risk groups of tumor recurrence as well as adverse effects risk groups.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/55fe5ce2dbf340ce9193c1484a1a434a Zobrazit plný text záznamu View record in DOAJ