SARS-CoV-2 Infection Concurrent with Acute Stroke: A Case Study of Aged People Partially Vaccinated Against COVID-19

Autor: Cristiane C. Bresani-Salvi, Clarice N.L. Morais, Maria de Fatima P.M. Albuquerque, Cynthia Braga, Jurandy J.F. Magalh?es, Suzannah Lant, Tom Solomon, Ana Catarina M. Ara?jo, Eduardo R.P. Aquino, Fl?via F. Albuquerque, Maria Lucia B. Ferreira
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Re:GEN Open, Vol 2, Iss 1, Pp 98-102 (2022)
Druh dokumentu: article
ISSN: 2766-2705
DOI: 10.1089/REGEN.2022.0022
Popis: Background: Elderly people have largely been vaccinated against severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) because of their higher risk of coronavirus disease 2019 (COVID-19). Little is known about the efficacy of such vaccines in elderly people with cerebrovascular diseases. Method: Here, we present the preliminary results of serology (IgA and IgG) and molecular testing for SARS-CoV-2 in a case series of elderly patients who were admitted with an acute stroke and had received a single dose of the COVID-19 vaccine in a city of northeastern Brazil. Currently, we are enquiring from 11 Brazilian neurology centers for their data and openly inviting groups that are working in this field to collaborate. Results: Between January 28 and March 25, 14 patients with acute stroke and ages within the vaccine age ranges were admitted to our neurology center. Ten patients had received their first dose of the COVID-19 vaccine. Most patients were women over 80 years of age with vascular risk factors and ischemic stroke. Three patients aged >85 years had no anti-SARS-CoV-2 antibodies detectable. Three other patients had SARS-CoV-2 infection, among whom a man died a few days later. Conclusion: These cases exemplify how elderly people with cerebrovascular diseases and incomplete vaccination schemes can be susceptible to COVID-19.
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