Evaluation of hepatic and kidney dysfunction among newly diagnosed HIV patients with viral hepatitis infection in Cape Coast, Ghana

Autor: Nsoh Godwin Anabire, William Jackson Tetteh, Dorcas Obiri-Yaboah, Isaac Annan, Arnold Togiwe Luuse, Paul Armah Aryee, Gideon Kofi Helegbe, Oheneba Charles Kofi Hagan, Sabastian Eliason
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-019-4513-8
Popis: Abstract Objective HIV positive individuals infected with viral hepatitis B (HBV) or C (HCV) are at an increased risk of progression to kidney and liver failures. Therefore, prior to initiation of antiretroviral therapy, early diagnosis and initiation of appropriate treatment protocols are imperative for co-infected individuals. This study evaluated the prevalence of HBV and HCV, and extent of liver and renal dysfunction among 90 newly diagnosed HIV patients attending the Cape Coast Teaching Hospital HIV clinic. Results Levels of alanine aminotransferase, aspartate-platelet ratio index and estimated glomerular filtration rate were used respectively to diagnose hepatotoxicity, liver fibrosis and chronic kidney disease (CKD). Association analyses were evaluated by Pearson’s Chi-square test or Fisher’s exact test and considered significant at p
Databáze: Directory of Open Access Journals
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