Vicinal difunctionalization of carbon–carbon double bond for the platform synthesis of trifluoroalkyl amines

Autor: Ferenc Béke, Ádám Mészáros, Ágnes Tóth, Bence Béla Botlik, Zoltán Novák
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19748-z
Popis: Metal-free olefin diamination may display challenges, especially when targeting fluorinated amines. Here, the authors report a double nucleophilic functionalization of an activated alkene originated from a trifluoropropenyliodonium salt with two nucleophiles for the selective synthesis of trifluoromethylated ethylene amines and diamines.
Databáze: Directory of Open Access Journals