Sphericity of lymph nodes using 3D-CT predicts metastasis in lung cancer patients

Autor: Kazuto Sugai, Yasuharu Sekine, Tomoyuki Kawamura, Takahiro Yanagihara, Yusuke Saeki, Shinsuke Kitazawa, Naohiro Kobayashi, Shinji Kikuchi, Yukinobu Goto, Hideo Ichimura, Yukio Sato
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Imaging, Vol 23, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 1470-7330
DOI: 10.1186/s40644-023-00635-x
Popis: Abstract Background The presence of mediastinal lymph node metastasis is important because it is related to the treatment and prognosis of lung cancer. Although prevalently used, evaluation of lymph nodes is not always reliable. We introduced sphericity as a criterion for evaluating morphologic differences between metastatic and nonmetastatic nodes. Methods We reviewed the cases of 66 patients with N2 disease and of 68 patients with N0-1 disease who underwent lobectomy with mediastinal dissection between January 2012 and December 2021. The sphericity of the dissected station lymph nodes, which represents how close the node is to being a true sphere, was evaluated along with the diameter and volume. Each parameter was obtained and evaluated for ability to predict metastasis. Results Metastatic lymph nodes had a larger short-axis diameter (average: 8.2 mm vs. 5.4 mm, p
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