Prooxidative-Antioxidant Regulation in Patients with Serous Meningitis
| Autor: | D.A. Zadiraka, O.V. Riabokon, O.O. Furyk, O.I. Hostischeva, O.M. Firiulina |
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| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Aktualʹnaâ Infektologiâ, Vol 4, Iss 2.11, Pp 155-159 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2312-413X 2312-4148 2312-413x |
| DOI: | 10.22141/2312-413x.2.11.2016.77663 |
| Popis: | Introduction. Serous meningitis takes a leading place among the central nervous system lesions, the share of which in neuroinfections structure ranges from 25 to 70 %. The imbalance in the functioning of prooxidant-antioxidant system plays a leading role in the damage of the nerve cells and leads to their death. Objective. To explore indicators of prooxidant-antioxidant regulation in the dynamics of the disease in patients with serous meningitis. Materials and methods. We observed 64 patients with serous meningitis at the age of 18 to 74 years old. Spectrophotometric method was used to determine the blood serum stable metabolites of nitric oxide — nitrites, spontaneous performance and metal-catalyzed oxidative protein modifications and catalase activity in the patients with serous meningitis. The control group consisted of 30 healthy individuals. Results. In the patients with serous meningitis at admission on the background of the dominance of clinical signs of general intoxication, cerebral, meningeal syndromes there were increased (p |
| Databáze: | Directory of Open Access Journals |
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