A case of irreversible bradycardia after rituximab therapy for diffuse large B-cell lymphoma

Autor:	Nway Le Ko Ko, Nareg Minaskeian, Hicham Z. El Masry
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Rituximab High grade AV block Complete AV block Bradyarrythmia Diffuse large B cell lymphoma Diseases of the circulatory (Cardiovascular) system RC666-701 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Cardio-Oncology, Vol 6, Iss 1, Pp 1-4 (2020)
Druh dokumentu:	article
ISSN:	2057-3804
DOI:	10.1186/s40959-020-00077-5
Popis:	Abstract This is a case of a middle-aged woman with underlying cardiac conduction system with episodes of AV Wenckebach, who subsequently developed significant AV conduction system abnormalities after receiving one standard dose of Rituximab infusion for diffuse large B-cell lymphoma. Rituximab, being a monoclonal antibody against CD-20 antigen, is effective in treatment of B-cell lymphoma but may also cause bradyarrythmias likely due to the calcium ion channel property of CD-20 antigen.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/55a56da09d594a70b46fb23dcfa8be81 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ