Association of polymorphisms in exon 6 and 3′-untranslated region of the OLR1 gene with milk production traits in Sahiwal cattle
| Autor: | Mohsin Ayoub Mir, Tavsief Ahmad, Ishwar Dayal Gupta, Ankit Magotra, Arun Pratap Singh, Manvendra Singh, Arif Pandit, Vineeth Muzhupilezhikethu Raveendran |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Applied Animal Research, Vol 51, Iss 1, Pp 156-165 (2023) |
| Druh dokumentu: | article |
| ISSN: | 09712119 0974-1844 0971-2119 |
| DOI: | 10.1080/09712119.2023.2167822 |
| Popis: | The present investigation was undertaken to explain the association of SNPs (single nucleotide polymorphisms) in exon 6 and 3′-UTR of OLR 1 gene with milk traits in Sahiwal cattle. Milk traits were observed from 328 Sahiwal cows sired by 64 bulls viz: – First lactation 305 days milk yield (Kg) (FL305MY), Average test day milk yield (Kg) (ATDMY), Average test day fat percentage (%) (ATDFP) and Lactational fat yield (Kg) (LFY). The animal model was used to estimate the breeding values for FL305MY and LFY. The traits ATDMY and ATDFP were corrected for significant non-genetic factors by using LSML-Harvey and subsequently used for association studies. A total of 130 animals for PCR-RFLP and 103 for sequencing were screened through three sets of primers for the presence of polymorphisms in exon 6 and 3′-UTR of the OLR1 gene. The CC genotype of SNP C337A in the 3′-UTR of OLR1 gene had a significant effect (p |
| Databáze: | Directory of Open Access Journals |
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