EFFICACY AND SAFETY OF LUSPATERCEPT VERSUS EPOETIN ALFA IN ERYTHROPOIESIS-STIMULATING AGENT (ESA)-NAIVE PATIENTS WITH TRANSFUSION-DEPENDENT LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS): FULL ANALYSIS OF THE COMMANDS TRIAL

Autor: G. Garcia-Manero, U. Platzbecker, V. Santini, A. Zeidan, P. Fenaux, R. Komrokji, J. Shortt, D. Valcarcel, A. Jonasova, S. Dimicoli-Salazar, I.S. Tiong, C.-C. Lin, J. Li, J. Zhang, A.C. Giuseppi, S. Kreitz, V. Pozharskaya, K. Keeperman, S. Rose, T. Prebet, A. Degulys, S. Paolini, T. Cluzeau, M. Della Porta
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Leukemia Research Reports, Vol 21, Iss , Pp 100447- (2024)
Druh dokumentu: article
ISSN: 2213-0489
DOI: 10.1016/j.lrr.2024.100447
Popis: Introduction: We report the full analysis of the COMMANDS trial assessing efficacy and safety of luspatercept versus epoetin alfa (EA) in ESA-naive patients with LR-MDS. Methods: 363 patients (aged ≥18 y, with transfusion-dependent LR-MDS, serum erythropoietin
Databáze: Directory of Open Access Journals