Electrocardiographic Pathological Findings Caused by the SARS-CoV-2 Virus Infection: Evidence from a Retrospective Multicenter International Cohort Longitudinal Pilot Study of 548 Subjects

Autor: Nicola Susca, Antonio Giovanni Solimando, Paola Borrelli, Donatello Marziliano, Francesco Monitillo, Pasquale Raimondo, Domenico Vestito, Agostino Lopizzo, Gaetano Brindicci, Mohammad Abumayyaleh, Ibrahim El-Battrawy, Annalisa Saracino, Salvatore Grasso, Natale Daniele Brunetti, Vito Racanelli, Francesco Santoro
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Cardiovascular Development and Disease, Vol 10, Iss 2, p 58 (2023)
Druh dokumentu: article
ISSN: 2308-3425
DOI: 10.3390/jcdd10020058
Popis: COVID-19 has threatened the capability of receiving and allocating patients in emergency departments (EDs) all over the world. This is a retrospective cohort study to explore the role of a simple procedure like an ECG to screen for the severity of COVID-19 on admission to the ED. For this study, 548 consecutive patients were enrolled in a multicenter international registry and stratified upon ECG on admission with a simple distinction between normal vs. abnormal rhythm. Among patients in the abnormal ECG group were those with heart rates higher than 100 beats per minute and/or atrial fibrillation. Survival in patients with normal ECG rhythm was deemed below 75% after 58 days and then stabilized, while survival in patients with abnormal ECG rhythm was deemed below 75% after 11 days and below 50% after 21 days. A multivariate analysis including abnormal rhythm, gender, age, diabetes, obesity, respiratory failure during hospitalization, heart failure during hospitalization, and abnormal rhythm was an independent predictor of death (HR 7.20 95% CI 3.63–14.28, p < 0.01). This finding, if confirmed in large prospective studies, is promising for identifying a cheap and simple procedure for patients in need of a closer look.
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