Accuracy of intravitreal injection volume for aflibercept pre-filled syringe and BD Luer-Lok one-milliliter syringe

Autor: John-Michael Guest, Brett Malbin, Gary Abrams, Anthony Parendo, Shibandri Das, Chinwenwa Okeagu, Bing X. Ross, Ashok Kumar, Xihui Lin
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Retina and Vitreous, Vol 8, Iss 1, Pp 1-5 (2022)
Druh dokumentu: article
ISSN: 2056-9920
DOI: 10.1186/s40942-022-00375-3
Popis: Abstract Background To evaluate the accuracy of intravitreal injection volume of the pre-filled syringe (PFS) in which aflibercept is packaged compared to the BD Luer-Lok 1-mL syringe. Methods Ophthalmologists injected their typical intravitreal volume for aflibercept using either the PFS or BD Luer-Lok 1-mL syringe for 5 times each. The injected fluid was weighed using a micro-scale and converted to volume. The volume of fluid injected was also evaluated when the 0.05 mL line on the PFS was lined up to the tip or base of the dome-shaped plunger. Results Injection volume was measured for 12 physicians. The average injected fluid volume was 74.22 ± 15.87 µL for PFS and 53.42 ± 4.61 µL for the BD Luer-Lok 1-mL syringe (p
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