Immune status and lymphocyte apoptosis in women with arterial hypertension and metabolic disturbances

Autor:	S. A. Frid, A. A. Karpov, I. A. Tuktarova, N. N. Kurchatova
Jazyk:	ruština
Rok vydání:	2008
Předmět:	arterial hypertension lymphocyte apoptosis insulin resistance Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Российский кардиологический журнал, Vol 0, Iss 3, Pp 22-26 (2008)
Druh dokumentu:	article
ISSN:	1560-4071 2618-7620
Popis:	Lymphocyte apoptosis and functional activity were studied in 60 women with arterial hypertension and metabolic disturbances (AH) and 60 women with isolated systolic AH (ISAH). Cell apoptosis was assessed by flow cytometry method (propidium iodide technique). In AH patients, in contract to ISAH participants, T and B-lymphocyte deficiency was observed, and lymphocyte proliferation after mitogenic stimulation was reduced. There was a substantial inverse correlation between peripheral blood lymphocyte count and various apoptosis markers, as well as apoptosis associations with the levels of insulin resistance, obesity and dyslipidemia in AH women.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5544358bbd764170b8c9eaef48d59c5c Zobrazit plný text záznamu View record in DOAJ