Vocal biomarker predicts fatigue in people with COVID-19: results from the prospective Predi-COVID cohort study

Autor: Lu Zhang, Guy Fagherazzi, Aurélie Fischer, Gloria Aguayo, Abir Elbéji, Eduardo Higa, Vladimir Despotovic, Petr V Nazarov
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMJ Open, Vol 12, Iss 11 (2022)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2022-062463
Popis: Objective To develop a vocal biomarker for fatigue monitoring in people with COVID-19.Design Prospective cohort study.Setting Predi-COVID data between May 2020 and May 2021.Participants A total of 1772 voice recordings were used to train an AI-based algorithm to predict fatigue, stratified by gender and smartphone’s operating system (Android/iOS). The recordings were collected from 296 participants tracked for 2 weeks following SARS-CoV-2 infection.Primary and secondary outcome measures Four machine learning algorithms (logistic regression, k-nearest neighbours, support vector machine and soft voting classifier) were used to train and derive the fatigue vocal biomarker. The models were evaluated based on the following metrics: area under the curve (AUC), accuracy, F1-score, precision and recall. The Brier score was also used to evaluate the models’ calibrations.Results The final study population included 56% of women and had a mean (±SD) age of 40 (±13) years. Women were more likely to report fatigue (p
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