Effects of Anti-Tuberculosis Drugs on Lipid Profile in Pulmonary Tuberculosis Patients
| Autor: | Nisar Ahmed, Iqra Amjad, Zain Abbas Malik, Abdullah Naseer, Mubashir Raza, Aqsa Imtiaz, Hina Awais, Talha Mannan, Adeel Ahmad |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of the Dow University of Health Sciences, Vol 16, Iss 2 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1995-2198 2410-2180 |
| DOI: | 10.36570/jduhs.2022.2.1235 |
| Popis: | Objective: To determine the anti-tuberculosis drugs effect on the lipid profile parameters in pulmonary tuberculosis (TB) patients. Methods: A prospective cross-sectional study was conducted at Tehsil Headquarter Hospital, Taunsa Sharif and District Headquarter Teaching Hospital, Dera Ghazi Khan from December 2020 to May 2021. The blood samples from 84 positive pulmonary TB patients were collected in three different intervals of the study, before the start of the treatment, and after the use of first four baseline drugs isoniazid (INH), rifampicin (RIF), pyrazinamide (PZA), and ethambutol (EMB) respectively to check out the variation in lipid profile parameters such as total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG) and very low density lipoprotein (VLDL). Results: Of 84 pulmonary TB patients, the mean age was 38.1 ± 19.8 years. There were 44 (52.4%) males and 40 (47.6%) females. The mean difference of cholesterol level significantly increases from baseline to 6th and 10th week, (p-value |
| Databáze: | Directory of Open Access Journals |
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