Independent effects of early life adversity on social cognitive function in patients with schizophrenia

Autor: Xing Peng, Wen-Peng Hou, Yu-Shen Ding, Qi Wang, Feng Li, Sha Sha, Chen-Chao Yu, Xiu-Jun Zhang, Fu-Chun Zhou, Chuan-Yue Wang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Psychiatry, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2024.1343188
Popis: ObjectiveThe aim of this study was to investigate the impact of early life adversity on cognitive function in patients with schizophrenia, with a focus on social cognition (SC).MethodsTwo groups of patients with schizophrenia were recruited and matched on sociodemographic and clinical characteristics. One group consisted of 32 patients with a history of childhood trauma (SCZ-ct), and the other group consisted of 30 patients without a history of childhood trauma (SCZ-nct). In addition, 39 healthy controls without a history of childhood trauma (HC-nct) were also recruited. The intelligence of the three groups was assessed using the Wechsler Abbreviated Scale of Intelligence (WAIS—RC) short version. The cognitive function evaluation was conducted using the MATRICS Consensus Cognitive Battery (MCCB), and early life adversity was measured using the Childhood Trauma Questionnaire-Short Form (CTQ) and Bullying Scale for Adults (BSA).ResultsPatients with schizophrenia endosed significantly higher scores on the CTQ (F=67.61, p
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