Graves disease is more prevalent than Hashimoto disease in children and adolescents with type 1 diabetes

Autor: Lu-Ting Wang, Chi-Yu Huang, Chao-Hsu Lin, Bi-Wen Cheng, Fu-Sung Lo, Wei-Hsin Ting, Yann-Jinn Lee
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Endocrinology, Vol 13 (2023)
Druh dokumentu: article
ISSN: 1664-2392
DOI: 10.3389/fendo.2022.1083690
Popis: IntroductionAutoimmune thyroid disease (AITD) is the most common associated autoimmune disorder in type 1 diabetes (T1D). Early detection of AITD is crucial to optimize glycemic control, growth, and intellectual development. In this prospective cohort study, we sought to characterize the prevalence, incident ages and risk factors of AITD in children and adolescents with T1D.Materials and methodsPatients with T1D diagnosed at ≤ 18 years at MacKay Children’s Hospital, Taipei, from 1990 to 2019 underwent annual screening for AITD. Institutional Review Board-approved data on age, sex, and disease profile are collected. Statistical analysis was performed by using independent sample t test for continuous variables, chi-squared test for categorical variables, and Kaplan-Meier estimates of cumulative incidence of AITD were calculated. A p value of
Databáze: Directory of Open Access Journals