Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling.

Autor: Sujuan Yan, Yamei Chen, Min Dong, Weizhong Song, Scott M Belcher, Hong-Sheng Wang
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: PLoS ONE, Vol 6, Iss 9, p e25455 (2011)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0025455
Popis: There is wide-spread human exposure to bisphenol A (BPA), a ubiquitous estrogenic endocrine disruptor that has been implicated as having potentially harmful effects on human heart health. Higher urine BPA concentrations have been shown to be associated with cardiovascular diseases in humans. However, neither the nature nor the mechanism(s) of BPA action on the heart are understood.The rapid (
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