| Autor: |
Yingzheng ZHANG, Peiyuan ZHUO, Ruhui LIN, Lidian CHEN |
| Jazyk: |
English<br />Chinese |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
康复学报, Vol 26, Pp 42-46 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2096-0328 |
| DOI: |
10.3724/SP.J.1329.2016.05042 |
| Popis: |
Objective:To investigate the effects of electroacupuncture (EA) at Baihui (DU20) acupoint on learning and memory ability and1H magnetic resonance spectroscopy (1H-MRS) in APP/PS1 transgenic mice.Methods:A male APP/PS1 transgenic mice mated with a wild type female mice and 15 bred APP/PS1 transgenic mice identified by PCR were randomly divided into the model group (n=7) and the EA group (n=8) according to a random number table, and 8 age-matched littermates were divided into the control group. The EA group received EA at Baihui acupoint for 4 weeks. Morris water maze was used to test spatial learning and memory ability in the fourth week. NAA, Glu of the hippocampus were detected by1H-MRS.Results:Compared with the model group, the level of NAA and Glu were significantly increased (PP |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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