Supplementation of Ampelopsis grossedentata extract contributes to the improvement of intestinal health in swine

Autor: Xiangyan Liu, Fusheng Zhang, Mengyao Li, Rong Li, Zhen Zhang, Juan Xu, Lixin Wen, Rongfang Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2024.1417309
Popis: IntroductionAmpelopsis grossedentata (vine tea), a high polyphenol content antioxidant plant resource, is renowned for its medicinal benefits. This study aimed to investigate the effects of Ampelopsis grossedentata extract (AGE) on anti-inflammatory and antioxidant ability, enhancement of intestinal immunity, improvement of intestinal structure, and regulation of gut microbiota in swine.MethodsA total of 135 weaned piglets were randomly divided into three groups: a control group, a low-dose group, and a high-dose group. Pigs were weighed and blood was collected on days 36, 85, and 154. The feed intake was recorded daily to calculate growth performance parameters. On day 154, five to six pigs in each group were randomly selected and euthanized to obtain a small intestine to investigate the effects of AGE on anti-inflammatory and antioxidant abilities and gut microbiota.ResultsThe results showed that 500 mg/kg AGE increased the expression of anti-inflammatory and immune cytokines (IL-10, IgG, and IgA) (p
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