Discovering Weighted Patterns in Intron Sequences Using Self-Adaptive Harmony Search and Back-Propagation Algorithms

Autor: Yin-Fu Huang, Chia-Ming Wang, Sing-Wu Liou
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: The Scientific World Journal, Vol 2013 (2013)
Druh dokumentu: article
ISSN: 1537-744X
DOI: 10.1155/2013/249034
Popis: A hybrid self-adaptive harmony search and back-propagation mining system was proposed to discover weighted patterns in human intron sequences. By testing the weights under a lazy nearest neighbor classifier, the numerical results revealed the significance of these weighted patterns. Comparing these weighted patterns with the popular intron consensus model, it is clear that the discovered weighted patterns make originally the ambiguous 5SS and 3SS header patterns more specific and concrete.
Databáze: Directory of Open Access Journals