Investigating the Role of Serum Hepcidin and Interleukin-6 in Non-Anemic Women with Acute Ischemic Stroke

Autor: Zahir Hussain
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Biomedicine, Vol 14, Iss 2, Pp 260-264 (2024)
Druh dokumentu: article
ISSN: 2158-0510
2158-0529
DOI: 10.21103/Article14(2)_OA3
Popis: Background: Hepcidin (HP) is an important regulator of iron homeostasis. Iron status and IL-6 have been shown to regulate the expression of HP. Serum iron (SI), HP, and IL-6 have a highly significant role in inflammation since inflammation elevates the levels of HP for expressing the ischemic condition. The present study was carried out to investigate the impact of an interactive association between HP, SI, and IL-6 in non-anemic women with acute ischemic stroke (AIS). Methods and Results: The present case-control, descriptive study comprised 25 non-anemic women with AIS and 25 healthy non-anemic women controls. The age range of AIS and control subjects was 50 to 54 years. Non-anemic AIS women within 8 hours after AIS onset (AIS0.05) in AIS-72 hrs. Linear regression expressed a high strength of the relationship between serum HP and SI for AIS
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