Alpha-lipoic acid induced insulin autoimmune antibody syndrome

Autor: Karthik Baburaj, Jabir MP, Vimal MV
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Egyptian Journal of Internal Medicine, Vol 36, Iss 1, Pp 1-3 (2024)
Druh dokumentu: article
ISSN: 2090-9098
DOI: 10.1186/s43162-024-00331-7
Popis: Abstract Background Insulin autoimmune antibody syndrome is an uncommon cause of hypoglycemia in non-diabetic individuals. We report a case of alpha-lipoic acid-induced insulin autoimmune antibody syndrome. Case report A 40-year-old non-diabetic female presented with unresponsiveness due to severe hypoglycemia. Investigations revealed high fasting insulin levels, elevated C-peptide, and positive anti-insulin antibodies. Further history revealed recent ingestion of alpha-lipoic acid supplements. She was diagnosed with alpha-lipoic acid-induced insulin autoimmune antibody syndrome and managed with symptomatic measures and steroids. Conclusions This case highlights the importance of recognizing drug-induced insulin autoimmune antibody syndrome as a potential cause of hypoglycemia in non-diabetic individuals, especially in the context of recent supplement or medication use.
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