Fatal Exacerbations of Systemic Capillary Leak Syndrome Complicating Coronavirus Disease

Autor: Patricia C. Cheung, A. Robin Eisch, Noble Maleque, Derek M. Polly, Sara C. Auld, Kirk M. Druey
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 27, Iss 10, Pp 2529-2534 (2021)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2710.211155
Popis: We report 2 fatal exacerbations of systemic capillary leak syndrome (SCLS), also known as Clarkson disease, associated with coronavirus disease (COVID-19) in the United States. One patient carried an established diagnosis of SCLS and the other sought treatment for new-onset hypotensive shock, hemoconcentration, and anasarca, classic symptoms indicative of an SCLS flare. Both patients had only mild-to-moderate symptoms of COVID-19. This clinical picture suggests that these patients succumbed to complications of SCLS induced by infection with severe acute respiratory syndrome coronavirus 2. Persons with known or suspected SCLS may be at increased risk for developing a disease flare in the setting of mild-to-moderate COVID-19 infection.
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